N-3-pyridylmethyl-N'-p-nitrophenylurea ocular toxicity in man and rabbits.
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N-3-pyridylmethyl-N'-p-nitrophenylurea ocular toxicity in man and rabbits.
Ingestion of the rat poison N-3-pyridylmethyl-N'-p-nitrophenylurea (PNU) produced ocular toxicity in three humans and in an animal model, the Dutch Belted rabbit. The electroretinogram b wave was especially susceptible to the effects of the rodenticide, and the target tissue appeared to be the retinal pigment epithelium. Injection of PNU itself did not produce ocular toxicity. The poison had to...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1988
ISSN: 0007-1161
DOI: 10.1136/bjo.72.8.584